Writing the book, literally, on bioelectronic medicine

Shocking twists: The adventures of the vagus nerve system are featured in a new book by the Cold Spring Harbor Laboratory Press, featuring the exploits of Feinstein Institute bioelectronic medicine researchers.
By GREGORY ZELLER //

The pioneering work of several key researchers has made Long Island a focal point in the emerging science of bioelectronic medicine – their combined knowledge and achievements could fill a book.

And it has. Fresh off the Cold Spring Harbor Laboratory Press comes “Bioelectronic Medicine: A Subject Collection From Cold Spring Harbor Perspectives in Medicine,” which belies that awkward academic title with a sharp and exciting focus: groundbreaking progress in bioelectronics, replete with impressive diagnostic and therapeutic applications.

Bioelectronic medicine uses cutting-edge device technology to monitor the electrical activity within the body’s nervous system, and to modulate it via highly targeted, very tiny shocks delivered directly to key nerve bundles.

Theories, research and clinical trials featuring breakthrough diagnostic and treatment options are piling up fast, and the book – officially published July 25 – summarizes recent developments “at the convergence of molecular medicine, neuroscience and biomedical engineering.”

Specifically, the page-turner highlights breakthroughs at Manhasset’s Feinstein Institute for Medical Research, retold here through an anthology of reprinted articles from “Cold Spring Harbor Perspectives in Medicine.”

“Perspectives” is an online publication of Cold Spring Harbor Laboratory, which has partnered frequently with the Feinstein Institute on bioelectronic business since 2015, when the two institutions announced a lab-to-clinic commercialization collaboration.

Kevin Tracey: Right on time.

The teamwork now includes the new book, which was co-edited by Feinstein Institute researchers Valentin Pavlov and Kevin Tracey, both globally recognized leaders in the bioelectronic medicine field.

Pavlov, a professor in the Feinstein Institute’s Center for Biomedical Science and Bioelectronic Medicine and in the Department of Molecular Medicine at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, currently explores the role of the all-important vagus nerve system in regulating inflammation and metabolism – very promising work for patients with sepsis and obesity-driven disorders.

Tracey, for all intents and purposes, is the father of bioelectronic medicine, heralded around the world as a preeminent expert in molecular-based inflammation and the leading innovator of the emerging bioelectronics field.

For the president of the Northwell Health system’s Manhasset-based research mecca, the publication of the new book comes not a moment too soon, with bioelectronic medicine – driven largely by lab work at the Feinstein Institute – evolving so quickly.

“Because publication drives science, it is timely for this book to showcase the rapid advances in the new field of bioelectronic medicine,” said Tracey, also a professor of molecular medicine and neurosurgery at the Zucker School. “The Cold Spring Harbor Laboratory Press produced an outstanding book promising significant impact for the field.”