TG it’s Friday: Long Island Craft Brew Week kicks off today at participating tap rooms and retailers. The event’s “drink it forward” feature offers the opportunity to trade two cans of food or other nonperishables for a can of specially brewed red ale. Much more as the week flows on, details here.
Please celebrate your social consciousness responsibly.
And don’t forget to vote for your favorite brewery in the state’s first-ever craft beer challenge, coming next week with a slate of judges led by Iron Chef Mario Batali.
Dicky Doo and the Don’ts recording of “Nee Nee Na Na Na Na Nu Nu” hit No. 40 on the Billboard charts on this day in 1958.
Happy birthday Yogi Berra, Katharine Hepburn and George Carlin. One of them said, “In America, anyone can become president. That’s the problem.” Which? Answer after you enjoy the news.
But first, this: Colorado scientists believe they’ve made a major breakthrough in understanding autoimmune diseases, those conditions like lupus, rheumatoid arthritis and multiple sclerosis in which the body’s defense system starts attacking itself.
Dozens of autoimmune conditions affect more than 20 million Americans, 80 percent of them women. There are treatments but no cures. And, trouble brewing, AI conditions are one of the most common side effects of the new immunotherapy cancer drugs.
The Colorado research centers on B Cells, the white blood cells that rush from your bone marrow to do battle with viruses and infections. Some B Cells get help from what are called T-bets, proteins that help the genetic material in our cells express itself. In autoimmune cases, T-bets significantly amplify the number and potency of certain B Cells, triggering the self-attack.
Block the host’s ability to produce the T-bets, and the B Cells act normally. The researchers, at National Jewish Health in Denver, did just that in lab mice, with pretty amazing results, not the least of which was that 90 percent of the rodents without T-bets lived longer than the control group.
Scientists have been studying how DNA translates to the cell level for decades, beginning with the Nobel Prize-winning research of Cold Spring Harbor’s Barbara McClintock in the 1950s. Nobel honors for unveiling the body’s genetic system of expression, called transcription, went to three French scientists in 1965.
Maybe this latest discovery will help pick up the pace.
Also on the research front: NYIT prof and gastric expert Aydin Farajidavar was celebrated by hundreds of gastroenterologists, hepatologists and other specialists at this year’s Digestive Disease Week, also known as “the world’s largest GI event.”
(Now there’s a mental picture.)
Farajidavar’s implantable gastric monitor is funded with a $457,000 National Institutes of Health grant. He’s also a 2015 Innovator of the Year.
But Henry Schein continued its streak of record-setting quarterlies.
And nothing phony about the numbers at Applied DNA Sciences.
Rentals under $3,500! The Babylon IDA suddenly got serious about affordable housing.
Taking stock: 60 years in, it appears that size, at least when it comes to housing, does matter.
Drop in: Northwell has a new behavioral health center designed to take some of the pressure off emergency services.
OK, maybe the commercials work: A record 239 million visitors traveled to New York State last year, generating an all-time high of $64.8 billion in direct spending, or the equivalent of one mediocre seat each for a performance of “Hamilton.”
Cool, clean, water: The Village of Ocean Beach (Suffolk County; had to check) is in line for $3.7 million in zero- or low-interest loans from the state for a new water supply well.
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Long Island’s Healthiest Companies: A new Innovate LI program recognizes local firms that promote workplace health and employee wellness. Nominations being accepted here now and mark your calendars for Sept. 13.
The rest of the Innovate calendar: Is here.
Let’s do tech out: Domino’s has launched autonomous delivery service in Hamburg using a six-wheeled robot designed by Starship Technologies, a European startup founded by two of Skype’s co-creators. Top speed is 10 mph, but it slows for pedestrians.
Birthday spot quiz: Had to be Carlin.
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Compiled by John Kominicki. Thanks for reading this far.