Luigi Aurisicchio

Science, numbers back Applied DNA’s COVID-19 serums

By GREGORY ZELLER // With scientists around the world racing toward a COVID-19 vaccine, serums manufactured by a Long Island biotech are showing significant promise – both medically and economically. Stony Brook-based Applied DNA Sciences and its lab partner, Italian innovator Takis Biotech, said this week that five linear-DNA based COVID-19 vaccine candidates developed by Takis and manufactured by Applied DNA “yielded strong antibody and T-cell responses” in laboratory mice, even at “very low doses”…


Gains on two fronts: Same-day test, virus ‘neutralizer’

By GREGORY ZELLER // An ambitious Long Island biotech is reporting exciting progress in a two-front battle against the raging novel coronavirus. Stony Brook-based Applied DNA Sciences on Tuesday announced that it has applied for FDA approval of its Linea COVID-19 diagnostic kit, which detects SARS-CoV-2 – the novel coronavirus that causes the COVID-19 disease – with same-day results. The announcement comes one day after Applied DNA and Italian biopharma Takis Biotech said the first…


LI biotech speeds COVID-19 vaccine candidates to Italy

By GREGORY ZELLER // With preliminary lab tests looking good, an innovative Long Island biotech is rushing a quintet of potential COVID-19 vaccines overseas. Stony Brook-based Applied DNA Sciences announced Wednesday that it has completed “design qualifications” and shipped five COVID-19 vaccine candidates to Italian biopharma Takis Biotech, a frequent collaborator working closely with Applied DNA to counter the coronavirus. The vaccine candidates were produced using the Stony Brook biotech’s proprietary, polymerase chain reaction-based LinearDNA…


Island firm speeds coronavirus vaccines toward tests

By GREGORY ZELLER // Just weeks after announcing an expanded international collaboration targeting the menacing novel coronavirus, Applied DNA Sciences is preparing to mass-produce four potential vaccines. Leveraging the Stony Brook-based biotech’s unique DNA-manufacturing abilities, Rome, Italy-based Takis Biotech will test potential vaccines against the coronavirus (now going by COVID-19) in laboratory mice, on a large scale. Applied DNA expects delivery of four DNA-based “preclinical vaccine candidates” from Takis this month, and “within weeks” will…


Applied DNA to speed up coronavirus countermeasures

By GREGORY ZELLER // Look out, coronavirus – Applied DNA is coming for you. Adding to its growing portfolio of cutting-edge Polymerase Chain Reaction-based projects, Stony Brook-based Applied DNA Sciences is expanding its Joint Development Agreement with Italian R&D company Takis Biotech, with the headline-making 2019-nCoV in their sights. Already hot on the trail of new cancer vaccines, the partners will now work on a “linear DNA” vaccine against the dreaded Wuhan, China-based illness that’s…


‘Linear DNA’ combo shows punch in cancer fight

By GREGORY ZELLER // Mark another impressive victory for LineaRX, this time in a two-front battle against cancer. The Stony Brook-based biotech with innovation in its DNA (literally) has lent its unique DNA-sequencing technology to two vaccine-candidate tests run by Italian R&D company Takis Biotech, which is hot on the trail of new therapeutic cancer vaccines. It might be catching up. On Thursday, LineaRX announced that both vaccines – each produced in “linear DNA” form…