No. 248: Cancer, flu and Alzheimer’s progress, less Time and please squeeze from the bottom

Happy Wednesday: Welcome new readers Bob, Craig, Gita, Phil and Elissa. Happy to have you all aboard.

John Rand received a patent for the collapsible toothpaste tube on this day in 1841. “Saturday Night Live” premiered in 1975 with George Carlin as guest host.

Happy birthday Henry John “57 Flavors” Heinz.

Leave the driving to them: Entrepreneur Kevin Bowker was schlepping a vanload of pals to a craft beer event one day, when inspiration hit. Transportation. Today, Bowker’s Tapped Enterprises runs a growing fleet of buses that get beer and wine tourists there and safely back again. (Sure beats the bank job.)

Perfect execution: Researchers at Northwell Health affiliate The Albert Einstein School of Medicine believe they’ve created a compound that causescancer cells to self-destruct — without affecting healthy cells — by triggering a kind of chemical suicide.

Everyone loves a club: i-hamptons, the upstart entrepreneur support network, has decided to go the paid membership route. Riptide, the organization’s $100,000 business plan pitchathon, debuts in November.

Where to work: The hottest IT jobs this year are information security analyst, software engineer and computer systems analyst, according to CareerCast’s annual jobs report, just out.

Sound education: Hofstra’s student-run record label released the EP “Allusions” from its first artist, IzzeYe, on Friday. It is available on multiple platforms, including Spotify and Apple Music.

Oh and: The university’s Women in Entrepreneurship Week event is set for Oct. 19, 4:30 to 6:30 p.m., with panel discussions, Q&A, and networking with women CEOs about challenges and opportunities in entrepreneurship. Pizza will be served. Register here.

Please write: Send tips, news, calendar items, pressers, promotions, job postings, birthdays, slings and arrows, carps, criticisms and corrections to

A few words from our sponsor: Farrell Fritz, a full-service law firm with 15 practice groups, advises startups on entity formation, founder and shareholder agreements, funding, executive compensation and benefits, licensing and technology transfer, mergers and acquisitions and other strategic transactions. The firm’s blog, New York Venture Hub, discusses legal and business issues facing entrepreneurs and investors.


From tough tech, with love: The Engine, the investment initiative founded by MIT to bridge the gap between discovery and commercialization by enabling startups to develop “tough” tech – breakthrough ideas that require time to commercialize – has hit $200 million in its first investment fund.

And: MIT wizards have invented technology that sees around corners.

Hope: This new Alzheimer’s test looks beyond a single problem gene.

Park in the ‘burbs: A new proposal for NYC mass transit involves integrating autonomous ride sharing with the city’s mass transit system and de-incentivizing private vehicle use.

Tractors to tech: Celebrating its 10th anniversary, 4-H National Youth Science Day is the world’s largest youth-led science challenge, reaching over 100,000 kids annually across all 50 states and doing everything from building robots to launching rockets to working with drones.

Missed the boat on sponsoring? Climb aboard. We need your support to keep this baby going.

The nocebo effect: The placebo effect’s evil twin can kick in when negative expectations steer our experience of symptoms and create conditions where none should occur. Meaning, yes, you can get side effects from a sugar pill.

Quote of the week: “The business we are in is to meet the unmet, unarticulated needs of customers. That’s what innovation is all about. And there is no way you’re going to do that without having empathy and curiosity.” – Microsoft CEO Satya Nadella


Radar, the NYC-based location platform for mobile apps, raised $2 million in seed funding led by Accel Partners, with participation from Expa and Fuel Capital.

+ Butterfly, a Brooklyn-based online platform that provides real-time leadership coaching, raised $2.4 million in seed funding. Backers included Daphni, Tectonic Ventures, Precursor Ventures and angel investors.

+ Phoenix-based Grateful Ventures, an online media and publishing company focusing on building lifestyle content and monetization strategies for high-influence food and cooking websites and bloggers, received a majority investment from Gannett Co.

+ Flu treatment developer Visterra tacked on another $23.6 million to its Series C funding from the Bill & Melinda Gates Foundation, MRL Ventures Fund, Vertex Venture Holdings Ltd., Polaris Partners, Flagship Pioneering, Omega Funds, Cycad Group and Alexandria Venture Investments.

+ Rhythm Pharmaceuticals, a Boston company developing treatments for rare metabolic disorders that cause obesity, has raised $120 million in its own upsized IPO.


Time change: Time Inc. is cutting frequency on such major titles as Entertainment Weekly, Sports Illustrated and Fortune. The Time magazine press run will also be reduced.

Getting its kicks: Iceland became the smallest nation ever to qualify for the World Cup. Its team beat Kosovo Monday night to win its qualifying group. Previously, no country with a population of less than 1 million had made it into the competition. Iceland? About 335,000.

Not going: The United States of America, for the first time in a generation.

Making a splash: The TWA terminal hotel at JFK will feature a rooftop pool.

Compiled by John Kominicki. Thanks for reading.